The latest update for the game, which introduced the Thieves Guild, also removed the dx9, dx10 and OpenGL renderers.
Until WINE gets proper DX11 support, the game is unplayable on Linux.
And from the looks of this thread: http://forums.elderscrollsonline.com/en/discussion/251561/no-longer-works-in-wine
It looks like they nuked the OpenGL renderer on Windows on purpose, so that Linux users could no longer play it.
It’s a Bethesda published game, after all!
You want to know the best part, they’re going to introduce DX12 instead of Vulkan.